4E-BP (eIF4E-BP) represses translation initiation by binding to the 5′ cap-binding protein eIF4E and inhibiting its activity. Although 4E-BP has been shown to be important in growth control, stress response, cancer, neuronal activity, and mammalian circadian rhythms, it is not understood how it preferentially represses a subset of mRNAs. We…[Read more]

This study was carried out to evaluate the

antiplasmodial activity of alcoholic and hydroalcoholic extract of

stem bark as well as the determination of core structure fractionated from its crude extract.

The antiplasmodial activity of stem bark extracts was investigated by

schizont maturation inhibition assay against…[Read more]