Although mitochondrial dysfunction appears to be a contributing factor in the pathogenesis of cardiovascular and metabolic diseases, empirical data on this association are still lacking. This study evaluated whether mitochondrial oxidative capacity, as assessed by phosphorus magnetic resonance spectroscopy, was associated with cardiovascular risk,…[Read more]

We conclude that RMR evolutionary trajectories are shaped by other processes than natural selection in this long-lived ectotherm.The transition of animal life from water onto land is associated with well-documented changes in respiratory physiology and blood chemistry, including a dramatic increase in blood pCO2 and bicarbonate, and changes in…[Read more]