3 worsening to 5.3 points improvement. DISCUSSION These virtual patient simulations, once validated against clinical data, could lead to better informed future clinical trial designs. © 2020 the Alzheimer’s Association.OBJECTIVE Citrullinated proteins are hallmark targets of autoantibodies in rheumatoid arthritis (RA). Our goal was to determine…[Read more]

BACKGROUND Aberrant expression of mucin-4 (MUC4) is present in a variety of human solid cancers, but the expression pattern of MUC4 and its clinical relevance in acute myeloid leukemia (AML) is unknown. We aimed to evaluate the expression level of MUC4 and explore its prognostic value in newly diagnosed adult patients with AML. METHODS Bone marrow…[Read more]