Our research culminated in the discovery of 25, which we propose as the preferred biochemical tool to interrogate cellular responses to GSTO1-1 inhibition.Using wave function (WF) in density functional theory (DFT) embedding methods provides a framework for performing localized, high-accuracy WF calculations on a system, while not incurring the…[Read more]

The increase of age and dietary energy increased the proportions of C181cis-9, C182n-6trans and monounsaturated fatty acid. In summary, the increase of age and dietary energy enhanced the intensity of metabolic changes and inflammatory responses. Akt targets Dietary energy and age affected the expressions of liver lipid metabolism-related genes,…[Read more]

The increase of age and dietary energy increased the proportions of C181cis-9, C182n-6trans and monounsaturated fatty acid. In summary, the increase of age and dietary energy enhanced the intensity of metabolic changes and inflammatory responses. Akt targets Dietary energy and age affected the expressions of liver lipid metabolism-related genes,…[Read more]