Using 13C-hyperpolarized MRS, respiration with different substrates, and enzyme assays, we localized this improvement to increased glutamate dehydrogenase activity. Finally, honokiol treatment increased ATP and PCr concentrations and increased total ATP synthesis flux in the T2D heart. In conclusion, hyperacetylation drives energetic dysfunction…[Read more]

001 each). In the PCG group, negative correlation was observed between VA and total densitometry (r=-0.49; P=0.004).

Patients with PCG and healthy subjects display differences in corneal densitometry and topographic measurements. PCG patients show greater corneal density with an inverse relationship between visual acuity and higher…[Read more]

001 each). In the PCG group, negative correlation was observed between VA and total densitometry (r=-0.49; P=0.004).

Patients with PCG and healthy subjects display differences in corneal densitometry and topographic measurements. PCG patients show greater corneal density with an inverse relationship between visual acuity and higher…[Read more]

001 each). In the PCG group, negative correlation was observed between VA and total densitometry (r=-0.49; P=0.004).

Patients with PCG and healthy subjects display differences in corneal densitometry and topographic measurements. PCG patients show greater corneal density with an inverse relationship between visual acuity and higher…[Read more]

001 each). In the PCG group, negative correlation was observed between VA and total densitometry (r=-0.49; P=0.004).

Patients with PCG and healthy subjects display differences in corneal densitometry and topographic measurements. PCG patients show greater corneal density with an inverse relationship between visual acuity and higher…[Read more]